ISSN:
0894-3230
Keywords:
calixarene sulphonates
;
amino acids
;
proteins
;
Chemistry
;
Theoretical, Physical and Computational Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
,
Physics
Notes:
The interactions of calixarene sulphonates with the basic amino acids arginine and lysine were studied by 1H NMR spectroscopy. Strong electrostatic binding occurs for calix[4]arene sulphonate with both lysine and arginine at pH 1 and 5. For the higher calixarenes, only weak interactions at the faces of the flattened macrocycles occur. This binding is in contrast to the inhibition of protein-protein interactions by the calixarenes where the calix[6]arene and calix[8]arene sulphonates show much stronger effects. © 1998 John Wiley & Sons, Ltd.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource