ISSN:
0899-0042
Keywords:
HPLC
;
bis(L-amino acid amidato)-copper(II) complexes
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A study developing enantiomeric separations by metal chelate additives to the mobile phase in reversed-phase liquid chromatography is reported. In particular the use of Cu(II) complexes of L-prolinamide (L-ProNH2) and L-valinamide (L-ValNH2) is examined and discussed. Interestingly, for a series of DNS-amino acids these selectors show higher enantioselectivity than that obtained with the corresponding nonderivatized amino acid-Cu(II) complexes.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/chir.530020311