ISSN:
0899-0042
Keywords:
enantiomeric separations
;
chiral stationary phases
;
chiral crown ether-type phases
;
guest-host complexation
;
phenylglycines
;
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The optical resolution of a series of 12 amino acids of the phenylglycine family was studied using a chiral crown ether column. The effects of pH, temperature, and mobile phase additive were investigated. In three examples it was confirmed that the R enantiomer eluted prior to the S enantiomer. Most phenylglycines were resolved with large separation factors; those with two functional groups substituents on opposing sides of the phenyl ring, however, were not well separated.
Additional Material:
4 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/chir.530020313
