ISSN:
0887-624X
Keywords:
poly(1,5-dioxepan-2-one)
;
crosslinking
;
bis(∊-caprolactone)
;
swelling behavior
;
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Poly(lactones) may be crosslinked by ring-opening polymerization of the corresponding cyclic esters in the presence of tetrafunctional bis(∊-caprolactone). The homopolymer of 1.5-dioxepan-2-one (DXO) has poor mechanical properties but also some very good properties, such as biocompatibility and degradability. Crosslinking of degradable polymer based on the poly(ether-ester) DXO was performed with crosslinkers having the same reactivity as the monomer. 2,2-Bis(∊-caprolactone-4-yl)propane (BCP) and bis(∊-caprolactone-4-yl) (BCY) with tetrafunctionalities were synthesized from the corresponding diols and then used as comonomers during the polymerization of DXO. The comonomers showed the same reactivity to the initiator, stanneous 2-ethylhexanoic acid, as DXO and perfectly random crosslinked films were obtained. The crosslinked films showed a high degree of swelling already at 2-3 mol % BCP or BCY. The BCP crosslinker was somewhat less soluble in DXO at lower temperatures, but all BCP was soluble at 180°C. These polymeric films were elastic with no crystallinity and the Tg values increased from -39°C for pure DXO to -35°C for BCP crosslinked films and -21°C for BCY crosslinked ones. © 1997 John Wiley & Sons, Inc. J Polym Sci A: Polym Chem 35: 1635-1649, 1997
Additional Material:
13 Ill.
Type of Medium:
Electronic Resource
