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Effect of PAF on erythrocyte membrane heterogeneity: A fluorescence study (1991)

Kantar, A. ; Giorgi, P. L. ; Curatola, G. ; [et al.]

Springer

Inflammation research 32 (1991), S. 347-350

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ISSN: 1420-908X

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract The effect of platelet activating factor, PAF, on the erythrocyte membrane heterogeneity was investigated by measuring the steady-state fluorescence anisotropy and fluorescence decay of 1-(4-trimethylammoniumphenyl)-6-phenyl-1,3,5-hexatriene (TMA-DPH) incorporated in hemoglobin-free erythrocyte membranes. PAF induced a significant increase of the lipid order in the exterior part of the membrane and a decrease in membrane heterogeneity. These results indicate that PAF may cause changes in the physico-chemical structure of the erythrocyte membrane.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01980897

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