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Mechanical parameters determined in dispersed ventricular heart cells (1987)

Niggli, E.

Springer

Cellular and molecular life sciences 43 (1987), S. 1150-1153

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ISSN: 1420-9071

Keywords: Myocardial contraction ; myocytes ; sarcomere length ; laser diffraction

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary A high-resolution laser diffration system suitable for studying the basic mechanical properties of small contractile single cells has been developed. This method was used to establish the mechanical behavior of 95 ventricular cells isolated from adult guinea pig hearts. During contraction, the sarcomere length shortened from 1828±43 nm (mean ±SD) to 1518±99nm. The maximal velocities were 1.98±0.64μm/s for shortening and 1.93±0.54 μm/s for re-lengthening. The twitch duration from 20% shortening to 80% re-lengthening was 622±120 ms.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01945514

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