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Lysosomal mutations increase susceptibility to anaesthetics (1989)

Ahmed, F. ; Lundin, L. -G. ; Shire, J. G. M.

Springer

Cellular and molecular life sciences 45 (1989), S. 1133-1135

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ISSN: 1420-9071

Keywords: Pentobarbital ; tribromoethanol ; alphaxalone ; sleeping time ; beige mutation ; reduced pigmentation gene ; mice

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary The anaesthetic responses of homozygous mutant mice were compared with those of their normal heterozygous littermates. The two recessive mutations studied were beige (bg) and reduced pigmentation (rp). Homozygosity for either significantly increased the sleeping time of both sexes after treatment with pentobarbital, tribromoethanol or the steroid anaesthetic alphaxalone.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01950180

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