ISSN:
1420-9071
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary It is shown that 2,3,4-triketo-tetrahydropyridine (I) exercises a diabetogenic activity on white rats when given in a dose of 80 mg/kg body weight. It is suggested that the group -COCOCONH- is responsible for this activity. This is in accordance with the observation that monoalkyl derivatives of alloxane show diabetogenic activity, while dialkyl derivatives show none.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02175524