ISSN:
1573-8353
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract 1-Alkoxy-2,2-bis(trifluoromethyl)aziridines containing an ester group in the α position of the alkoxy substituent undergo nucleophilic substitution (ammonolysis and hydrolysis) with retention of the aziridine ring. The corresponding carboxylic acids, which were separated to give the antipodes with an optical purity of 95% through the diastereomeric salts with R- and S-α-phenylethylamine, were obtained.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00504109