ISSN:
1573-8353
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract 1-Acetyl-5-(3-indolyl)pyrazoline and 1-phenyl-5-(3-indolyl)pyrazoline were obtained by the reaction of β-(1-acetyl-3-indolyl)acrylaldehyde with hydrazine hydrate and phenylhydrazine, respectively, in the presence of acetic acid with subsequent alkaline hydrolysis. The dehydration of the indole derivatives of pyrazoline was studied. α-Bromo-β-(1-acetyl-3-indolyl)acrylaldehyde, which gives 3(5)-(3-indolyl)pyrazole and 1-phenyl-5-(1-acetyl-3-indolyl)pyrazole with hydrazine hydrate in alcohol and phenylhydrazine in acetic acid, respectively, was obtained by the addition of bromine to β-(1-acetyl-3-indolyl)acrylaldehyde and dehydrobromination of the addition product.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00476783
