ISSN:
1573-899X
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Conclusions 1. Administration of L-dopa in a dose of 20 mg/kg for 12 days leads to the premature onset of puberty in sexually immature female rats. 2. Administration of L-dopa in a dose of 100 mg/kg daily for 12 days inhibits the onset of puberty in sexually immature female rats. 3. Administration of L-dopa in a dose of 20 mg/kg daily for 3–4 weeks inhibits ovulation and causes an increase in the LH content in the pituitary of young sexually mature female rats. 4. L-dopa, when injected into rats with an irregular anovulatory cycle in a dose of 20 mg/kg (daily for 2 weeks) causes ovulation, alters the ratio between the phases of estrus and diestrus, and also changes the FSH and LH levels in the pituitary in 50% of cases. 5. Injection of L-dopa in a dose of 20 mg/kg into rats with spontaneous estrus restores their normal sex cycle and ovulation.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01186055
