ISSN:
1573-9171
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Conclusions The reaction of Δ16-20-ketopregnenes with mesitylenesulfonylhydroxylamine leads to 17a-aza- and 17-aza-D-homoandrostanes with an amidine fragment in the D ring and proceeds through a sequence of steps involving the initial attack of the reagent at the 20-keto group, a Beckmann rearrangement of the 20-mesityl-sulfonyloxime formed to Δ16-17-acetylaminoandrostene which undergoes a new regioselective cationotropic rearrangement to give steroid amidines.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00955790