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Effect of polynucleotides on the dimerization of glycine (1981)

Mizutani, Hiroshi ; Ponnamperuma, Cyril

Springer

Origins of life and evolution of the biospheres 11 (1981), S. 237-241

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ISSN: 1573-0875

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Geosciences

Notes: Abstract Polynucleotides were found to suppress the dimerization reaction of aqueous glycine with trimetaphosphate as the condensing agent. Small anions (chloride, acetate, and phosphate) did not show this effect. The reaction was studied at a pH of about 11.5 and at 70°C and room temperature with a 13 mM concentration of glycine and trimetaphosphate. Under these conditions, the effect of the polynucleotides was in the following order: polyguanylic acid 〈 polycytidylic acid 〈 polyadenylic acid 〈 polyuridylic acid. The result may have a significant implication for the understanding of processes of chemical evolution.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00931389

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