ISSN:
1573-8221
Keywords:
heterografted tumors
;
chemotherapy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Experiments with explants of human melanomas cultivated in diffusion chambers in the peritoneal cavity of mice (10 cases) and explants into the retrobuccal pouches of golden hamsters (5 cases) revealed marked individual differences in the sensitivity of these tumors to combined treatment with three therapeutic preparations: vincristine (or vinblastine), nitrosomethylurea, and actinomycin D. Comparison of the results obtained in these two series of investigations showed agreement in three of five cases. In two cases the positive result obtained in the experiments with diffusion chambers corresponded to a negative result in the experiments on hamsters.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00801085
