ISSN:
1573-7365
Keywords:
γ-aminobutyric acid (GABA)
;
hepatic encephalopathy
;
neurotransmission
;
receptor binding
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract The specific binding of γ-aminobutyric acid (GABA) to synaptic membranes prepared from the brains of rats with acute liver failure due to portacaval shunt and hepatic artery ligation was measured. No changes in the affinity or the density of the low- and high-affinity binding sites of the GABA receptor were observed, indicating that this model of acute hepatic encephalopathy is apparently not associated with altered GABAergic neurotransmission.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00999610