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The Peripheral Benzodiazepine Receptors: A Review (2000)

Beurdeley-Thomas, Arnaud ; Miccoli, Laurent ; Oudard, Stephane ; [et al.]

Springer

Journal of neuro-oncology 46 (2000), S. 45-56

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ISSN: 1573-7373

Keywords: PBR ; associated proteins ; PRAX-1 ; cell differentiation ; cancer ; steroid biosynthesis

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract Peripheral benzodiazepine receptors (PBRs) have been identified in various peripheral tissues as well as in glial cells in the brain. This review describes the tissue and subcellular distribution of the PBR in mammalian tissues and analyzes its many putative endogenous ligands. It deals with the pharmacological, structural and molecular characterization of the PBR, the proteins associated with the receptor (VDAC, ANC, PRAX-1) and their roles in cell growth and differentiation, cancer, steroid biosynthesis, and other physiological roles.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1023/A:1006456715525

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