ISSN:
1573-7373
Keywords:
low-grade non-Hodgkin's lymphoma
;
leptomeningeal involvement
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary We present the case of a 56-year old man who developed -at the age of 46-paraesthesia and numbness in the perianal region, the feet and lower legs accompanied by the presence of B-lymphocytes in the cerebrospinal fluid (CSF). Despite intensive work-up an explanation was not found until he developed hepato-splenomegaly ten years after the initial symptoms. Haematologic evaluation at that time disclosed a low-grade malignant B-cell lymphoma. Repeated CSF examination revealed 31 leukocytes/mm3, of which were mainly lymphocytes. These proved to be B-lymphocytes of monoclonal origin. These findings suggest that a leptomeningeal localisation of a low-grade malignant lymphoma had been present for ten years before systemic manifestation of the disease.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02341158