Electronic Resource
Springer
Neurochemical research
1 (1976), S. 47-52
ISSN:
1573-6903
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract 3-Methoxy-4-hydroxymandelic acid (VMA) is transported into the isolated choroid plexus against a concentration gradient by a saturable, energy-dependent system. The apparentK m for transport is 35 nM and theV max is 1 pmol/mg tissue/hr. Concentrations of probenecid (0.1 mM) that block the transport of other acidic biogenic amine metabolites did not block the transport of VMA. The transport system of the choroid plexus probably plays a role in clearing VMA from the CSF.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00965630
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