ISSN:
1432-0428
Keywords:
Keywords Insulin
;
glucose tolerance
;
vitamin D
;
elderly.
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Vitamin D status was assessed in 142 elderly Dutchmen participating in a prospective population-based study of environmental factors in the aetiology of non-insulin-dependent diabetes mellitus. Of the men aged 70–88 years examined between March and May 1990, 39 % were vitamin D depleted. After adjustment for confounding by age, BMI, physical activity, month of sampling, cigarette smoking and alcohol intake the 1-h glucose and area under the glucose curve during a standard 75-g oral glucose tolerance test (OGTT) were inversely associated with the serum concentration of 25-OH vitamin D (r = −0.23, p 〈 0.01; r = −0.26, p 〈 0.01, respectively). After excluding newly diagnosed diabetic patients total insulin concentrations during OGTT were also inversely associated with the concentration of 25-OH vitamin D (r = −0.18 to −0.23, p 〈 0.05). Hypovitaminosis D may be a significant risk factor for glucose intolerance. [Diabetologia (1997) 40: 344–347]
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s001250050685
