ISSN:
1432-1912
Keywords:
Blood viscosity
;
Red cell deformability
;
Pentoxifylline
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Using a hyperosmolar erythrocyte model, the authors studied the effect of changes in red cell deformability on whole blood viscosity and investigated the possibility of using pentoxifylline to modify red cell deformability and whole blood viscosity. In vitro studies reveal a significant correlation between the two parameters in as much as they are inversely proportionate, i.e. viscosity increases as red cell deformability decreases and vice versa. Addition of pentoxifylline improves impaired red cell deformability under hyperosmolar conditions and simultaneously produces a reduction in whole blood viscosity.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00498562
