ISSN:
1432-2072
Keywords:
Touch-sensitive device
;
Visual attention
;
Cognition
;
Amphetamine
;
Serotonin
;
5-HT
;
Acetylcholine
;
Rat
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract A multiple choice serial reaction time task was used to investigate visual attention in rats. The intelligence panel consisted of a transparent touch-sensitive device, placed directly in front of a video monitor. Amphetamine (0.2–1.6 mg/kg IP) increased errors of omission and decreased latency to respond, but had no effect on accuracy. The 5-HT agonist quipazine (0.6–2.4 mg/kg IP) increased errors of omission, but did not affect other parameters. ICV administration of hemicholinium-3 (1–4 µg) had no effect upon performance. Thus, psychopharmacological manipulations can reliably alter performance in the touch window box, suggesting potential new avenues for rat cognitive testing.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02245846
