ISSN:
1432-1106
Keywords:
Bradykinin
;
Tooth-pulp
;
Cortical neuron
;
Coronal gyrus
;
Cat
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The properties of single cortical neurons responding to electrical stimulation of the tooth-pulp and to intrapulpal application of bradykinin were studied in the cat. The activities of tooth-pulp driven neurons (TPNs) were recorded from the middle and anterior parts of the coronal gyrus of the cerebral cortex. Bradykinin-sensitive tooth-pulp driven neurons (BK-TPNs) were located in layer IV of area 3b of the anterior part of the coronal gyrus. These neurons had a large cutaneous oro-facial receptive field and received a nociceptive input from the facial skin as well as from the tooth-pulp. The BK-TPNs had a higher threshold and longer latency to electrical stimulation than TPNs insensitive to bradykinin (non BK-TPNs). These findings suggest that BK-TPNs in this cortical area may be involved in sensory processing of noxious information from trigeminal regions.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00243318
