ISSN:
1432-1041
Keywords:
Bendroflumethiazide
;
diuretics
;
GLC
;
thiazides
;
plasma level
;
pharmacokinetics
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary A GLC method for determination of bendroflumethiazide has been developed, using extractive methylation. Cyclopenthiazide was used as internal standard. The maximal plasma concentration (56–107 ng/ml) after bendroflumethiazide 10 mg given orally to four healthy volunteers was seen at 2–2.5 h. On the slope between 4 and 10 h T1/2 averaged 2.7 h.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00558343