ISSN:
1432-1920
Keywords:
Key words MELAS
;
Single-photon emission computed tomography
;
Cerebral blood flow
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract We report cerebral SPECT studies on two siblings with the syndrome of mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS). Tc-99m HMPAO brain SPECT was performed 8, 19 and 30 days after a stroke-like episode in one case and 10 days after a stroke-like episode, 6 h after a partial seizure and as a follow-up study in the other. Increased blood flow was seen in both these patients with stroke-like episodes due to MELAS. The cause of the increased blood flow is uncertain, but it may be related to the decreased pH created by local increase in lactic acid.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s002340050005
