ISSN:
1434-0879
Keywords:
Urothelium
;
Electron microscopy
;
Verapamil
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The effect of single or multiple instillations of high verapamil concentrations on the cytoarchitecture of the bladder epithelium was assessed by electron microscopy. Ruthenium red was used to evaluate the surface mucopolysaccharide coats and the integrity of junctional complexes between luminal or nonluminal cells was found in any experimental animals, nor was there a breakdown of the junctional complexes between luminal cells. These data suggest that verapamil may be safely used intravesically as adjunct to standard chemotherapy.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00261582