ISSN:
1432-1211
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Medizin
Notizen:
Abstract Partial N-terminal amino acid sequences of the Ia molecule encoded by theI-E orI-C (I-EC) subregion of theH- 2d haplotype are presented. Several homology relationships are apparent when these sequences are compared to the gene products of the mouseI- ECk andI-A subregions and to their human and guinea pig counterparts. Theβ polypeptide differs from the EC β k polypeptide in two of the seven positions at which they can be compared and shows moderate homology with its human p29 counterpart. Theα polypeptide is identical to the EC α k polypeptide in the eight positions which can be compared and is highly homologous to the human p34 polypeptide. The genetic implications of these observations are discussed.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF01563904