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99mTc-HMPAO as a tumour blood flow agent (1987)

Hammersley, Peter A. G. ; McCready, V. Ralph ; Babich, John W. ; [et al.]

Springer

European journal of nuclear medicine 13 (1987), S. 90-94

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ISSN: 1619-7089

Keywords: Tumours ; Blood flow ; Propranolol ; Anaesthesia

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract The cerebral blood flow agent, 99mTc-HMPAO (‘CeretecTM’) has been investigated to see if it can be used to estimate tumour blood flow. Its distribution in Balb/c mice bearing either a subcutaneously implanted sarcoma or a plasmacytoma has been shown to be similar to that of 86RbCl. The changes in peripheral blood flow caused by the beta-blocker, propranolol, and by Nembutal anaesthesia, are manifested equally by 99mTc-HMPAO and 86Rb. We conclude, therefore, that HMPAO may be useful in estimating tumour perfusion.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00256023

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