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  • 1
    ISSN: 1432-0584
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Female Wistar rats with autotransplanted and xenotransplanted skingrafts received3H-Thymidin 3 times daily for 9 days after grafting. Qualitative and quantitative analysis of the lymphocytes in the peripheral blood were done daily. The grafted skin was examined histologically and autoradiographically on the 9th day. There was a significant difference in the labelling index of small lymphocytes between xenotransplanted and autotransplanted animals. The labelling of lymphocytes in the animals with xenografts was higher from the 6th day on as compared to the animals with autografts. From these results the conclusion was drawn, that more small lymphocytes are formed in animals with xenografts. The lymphocytes enter and leave the blood stream at an increased rate.
    Notes: Zusammenfassung Autotransplantierte und xenotransplantierte weibliche Wistar-Ratten erhielten vom Tage 0 bis zum Tage+9 dreimal täglich3H-Thymidin. Qualitative und quantitative Analysen der Lymphozyten-Population des peripheren Blutes wurden täglich durchgeführt, die Hauttransplantate histologisch und autoradiographisch am Tage+9 untersucht. Die Ergebnisse zeigen, daß der Markierungsindex der kleinen Lymphozyten in Blut zwischen xenotransplantierten und autotransplantierten Tieren signifikant verschieden ist, wobei die Markierung bei der Gruppe mit Xenotransplantaten ab dem 6. Tage höher liegt als bei den autotransplantierten Kontrolltieren. Die Ergebnisse lassen auf eine erhöhte Bildungs-, Einstrom- und Ausstromrate kleiner Lymphozyten nach Xenotransplantation schließen.
    Type of Medium: Electronic Resource
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