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  • 1
    Electronic Resource
    Electronic Resource
    Mutations in ADE3 reduce the efficiency of the omnipotent suppressor sup45-2 (1989)
    Springer
    Current genetics 16 (1989), S. 315-321 
    Details
    ISSN: 1432-0983
    Keywords: Saccharomyces cerevisiae ; Antisuppressor ; ADE3 ; Translation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Mutations in a known yeast gene, ADE3, were shown to act as an antisuppressor, reducing the efficiency of the omnipotent suppressor, sup45-2. The ADE3 locus encodes the trifunctional enzyme C1-tetrahydrofolate synthase, which is required for the biosynthesis of purines, thymidylate, methionine, histidine, pantothenic acid and formylmethionyl-tRNAfmet. The role of this enzyme in translational fidelity had not previously been suspected.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00340709
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