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Biosynthesis of rutacridone in tissue cultures of Ruta graveolens L. (1982)

Baumert, A. ; Kuzovkina, I. N. ; Krauss, G. ; [et al.]

Springer

Plant cell reports 1 (1982), S. 168-171

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ISSN: 1432-203X

Source: Springer Online Journal Archives 1860-2000

Topics: Biology

Notes: Abstract The dihydrofuroacridone, rutacridone, is the main alkaloid in tissue cultures of Ruta graveolens L. strain R-19. The biosynthesis of this particular acridone alkaloid was investigated by using calluses and suspension cultures of strain R-19. Anthranilic acid is specifically incorporated into ring A of rutacridone. Some further evidence was provided that acetate via a polyketide is involved in acridone biosynthesis. Mevalonic acid gave a poor incorporation into rutacridone. Thus the origin of the isopropyldihydrofuran moiety of the investigated alkaloid is still obscure.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00269190

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