ISSN:
1432-203X
Keywords:
Catharanthus roseus
;
Acetylsalicylic acid
;
Aspirin
;
Alkaloids
;
suspension cultures
;
tumor
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary Addition of various concentrations (0.5–20 mM) of acetylsalicylic acid (ASA) to tumor lines ofCatharanthus roseus cultivatedin vitro and requiring corn starch as carbon source, produced remarkable effects on secondary metabolite production. An increase of 505% total alkaloids per culture (cells plus liquid medium), 1587% total phenolics (liquid medium), 612% total furanocoumarins (liquid medium) and 1476% total anthocyanins (liquid medium) was detected. 1 mM ASA in combination with other elicitors, such as homogenates ofAspergillus fumigatus or trans-cinnamic acid, did not further increase the metabolite content substantially. The results suggest that ASA could act as a new biotic elicitor of metabolite production inC. roseus cell suspension culture.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01088282
