ISSN:
1432-203X
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract The efficacy of 2′-deoxyguanosine (GdR) on the induction of binucleate cells in onion root tips was studied. GdR inhibits plant cytokinesis during the last part of the mitotic period. Apparently, this deoxynucleoside causes a considerable slowing down in the mitotic rate (50%) and also has a slight effect as an inhibitor of cytokinesis (30%). The effect on the mitotic rate was established with 1 mM colchicine (metaphase rate) and with 5 mM caffeine (telophase rate). Since 1 mM GdR has a remarkable potentiating action on inhibition of cytokinesis by caffeine, we postulate that GdR, or a phosphorylated derivative from it, inhibits cytokinesis by a similar mechanism as caffeine. According to our postulation, GdR interferes with a certain ATPase activity required for membrane fusion of the Golgi vesicles during plant cytokinesis.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00269331
