ISSN:
1432-1084
Keywords:
Lung
;
MR studies/ magnetic resonance (MR), contrast enhancement
;
Magnetic resonance (MR), rapid imaging
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract A FLASH technique was used, which encompassed the entire thorax in the transverse plane, before and after dynamic intravenous injection of godalinium DTPA (Gd-DTPA) to study 7 patients with normal lungs, 12 patients with interstitial lung disease (ILD), and 11 patients with pulmonary nodules. Comparative CT studies were obtained within 2 weeks of the MRI study in the patients with lung disease. Quantitative signal intensity (SI) measurements were performed. Qualitative evaluation of lung parenchyma was determined in a prospective blinded fashion, and in the normal group comparison was made with the CT images. In normal patients, SI of lung parenchyma increased by 7.7 ± 1.3%. On precontrast images, second-order pulmonary branchings were visible while post-contrast, fifth-to sixth-order branches were apparent. In patients with ILD, interstitial changes enhanced to a variable ] substantial (308.4%). Detection of pulmonary nodules improved following contrast injection. The minimum lesion size detectable decreased from 8 mm precontrast to 5 mm post-contrast. Percentage contrast enhancement was greater for malignant nodules (124.2 ±79.7%) than benign nodules (5.8 ± 4.7%)(p〈0.01). Society of North America, 1–6 December 1991, Chicago
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00187555
