ISSN:
1432-0533
Keywords:
Lafora disease
;
Myocardium
;
Deposits
;
Enzame histochemistry
;
Electron microscopy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Histological, histochemical and electron microscopic studies on the myocardium of 3 Japanese patients with Lafora disease were carried out. Deposits in the myocardium stained positively with PAS, Best's carmine and Lugol's indine. After digestion of the sections with α-amylase, the deposits disappeared or were less intense, in particular with PAS staining. Phosphorylase activity was deficient in the myocardium of Case 3, when compared with controls, both of which were kept frozen at −20°C following autopsy. Electron microscopy revealed that the deposits were not membrane-bound and consisted of fine particles and fibrillae. The nature of the deposits is diseussed.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00686166
