ISSN:
1432-0533
Keywords:
Sensory neuropathy
;
Nerve biopsy
;
Electron microscopy
;
Quantitative study
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary An electron microscope study and quantitation of myelinated and unmyelinated fibers of seven nerve biopsies performed in sporadic cases of idiopathic sensory neuropathy is reported. The number of myelinated fibers is markedly decreased or absent in every case. On the contrary, the unmyelinated fiber numbers are normal or increased. In most cases, the small diameter myelinated and unmyelinated fibers proportions are higher than those of control biopsies. The electron microscope study discloses evidence of degeneration of Wallerian type and regeneration is also indicated by quantitative studies. Regenerative phenomena seem more obvious in sporadic cases than in previously reported studies of familial cases.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00684814