ISSN:
1432-0533
Keywords:
Neurons
;
Thalamus
;
Inclusions
;
Ultrastructure
;
Myotonic dystrophy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Intracytoplasmic cosinophilic inclusions were found by light microscopy in the thalamic neurons of 35 consecutive normal adult brains and in a case of myotonic dystrophy, but not in six newborn children, including one with myotonic dystrophy. Histochemical tests suggested a protein composition. Ultrastructurally, the inclusions were composed of stacks of parallel alternating dark and light rectilinear profiles not surrounded by a limiting membrane. Such inclusions are a virtually constant finding in the adult human thalamus and probably represent sites of neuronal protein storage.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00688015