ISSN:
1432-0711
Keywords:
Key words: Photodynamic therapy
;
Gynecological malignancy
;
m-THPC
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract. 4 patients with recurrent gynecological malignancy were treated photodynamically, 4 d after sensitisation with intravenous meso-tetra(hydroxyphenyl)chlorin (m-THPC) at a dose of 0.15 mg/kg bodyweight (total dose ranged from 12–15 mg). Light at 652 nm was derived from a KTP-Dye laser (Diasonic) and delivered superficially at a total light dose of 20 J/cm2 (power density of 100 mW/ sec). Within 24 h necrosis occurred which was restricted to the tumor area. There was serious bleeding occurred in 1 patient. All tumors responded to PDT, however woundhealing was significantly delayed and survival times were disappointingly short.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s004040050249
