ISSN:
1432-119X
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary Changes in liver enzymes of Weanling CDF1 mice inoculated with mouse hepatitis virus (MHV3) were studied by histochemical techniques for the demonstration of alkaline phosphatase, acid phosphatase, and esterase. Marked changes were observed in the distribution of these enzymes 22 to 70 hours after infection. These included a generalized increase in peribiliary alkaline phosphatase together with a localized increase in acid phosphatase and a decrease in esterase associated with parenchymal damage and subsequent necrosis. Thus the effect of a virus infection upon a given tissue can be revealed and characterized by histochemical techniques.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00736423
