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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 157 (1998), S. S127 
    ISSN: 1432-1076
    Keywords: Key words Hyperhomocysteinaemia ; Arteriosclerosis ; Venous thrombosis ; Treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Convincing evidence of moderate hyperhomocysteinaemia as a risk factor for vascular disease has accumulated within the last decade being independent of conventional risk factors and equally strong as hypercholesterolaemia and smoking. A synergistic interaction with hypertension and smoking in their joint arteriosclerotic effect in patients is demonstrated which makes the result of homocysteine-lowering intervention very promising, especially in those vascular patients with an association of these risk factors. Conclusion Despite the proven homocysteine-lowering effect of intervention with sample, safe, and cheap vitamin regimen, no data are so far available on the clinical outcome of such treatment. Clinical trials to demonstrate a hopefully beneficial result of homocysteine reduction are urgently needed.
    Type of Medium: Electronic Resource
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