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The human PGM-2 and its chromosomal localization in man-mouse hybrids (1977)

Wijnen, Lucie M. M. ; Grzeschik, K. -H. ; Pearson, P. L. ; [et al.]

Springer

Human genetics 〈Berlin〉 37 (1977), S. 271-278

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ISSN: 1432-1203

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary A detailed procedure is described for a rapid detection of phosphoglucomutase-2 (=phosphopentomutase; PGM-2) on Cellogel following electrophoresis of extracts of human red blood cells and other tissues, including cultured fibroblasts and various types of primate-rodent somatic hybrid cells. The present study indicated that there is only one locus for phosphopentomutase in man. The data from a selected panel of 20 independent clones of man-mouse somatic cell hybrids, investigated for the presence of human chromosomes and for the presence or absence of human PGM-2 favored the assignment of the human PGM-2 locus to chromosome 4.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00393608

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