ZIB

Hits per page

hit 1 - 1 | 1 hit

Select All Export

Electronic Resource

Detection of laser-UV microirradiation-induced DNA photolesions by immunofluorescent staining (1980)

Cremer, C. ; Cremer, T. ; Fukuda, M. ; [et al.]

Springer

Human genetics 〈Berlin〉 54 (1980), S. 107-110

add to mindlist on the mindlist

Details

ISSN: 1432-1203

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine

Notes: Summary A low-power laser-UV microbeam of wave-length 257 nm was used for microirradiation of a small part of the nucleus of Chinese hamster cells. Following fixation in interphase or in the subsequent metaphase indirect immunofluorescent staining was performed with antiserum to photoproducts of DNA treated with far UV light. The results show that antibodies specific for UV-irradiated DNA can be used for a direct detection of laser-UV microirradiation-induced DNA photolesions. The potential usefulness of this method for investigation of the spatial arrangement of chromosomes in the interphase nucleus is discussed.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00279058

Library	Location	Call Number	Volume/Issue/Year	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

hit 1 - 1 | 1 hit