ISSN:
1432-0878
Schlagwort(e):
Neurosecretory cells
;
Rat
;
Cytoplasmic bodies resembling nucleoli
;
Paranucleolar and coiled bodies
Quelle:
Springer Online Journal Archives 1860-2000
Thema:
Biologie
,
Medizin
Notizen:
Summary A distinctive cytoplasmic inclusion, termed nucleolus-resembling body, was identified in the neurons, but not in the glial cells, of the medial vascular prechiasmatic gland, the preoptic recess and the anterior part of the suprachiasmatic area in the rat. This ultrastructure which lacks a limiting membrane is made of an entanglement of tightly packed filaments, 60–70 Å in diameter. Each filament consists of smaller units, 15–20 Å thick. Usually, only one such ultrastructure is present in a cell, but at time two were identified. It is present in most neurosecretory cells. It is surrounded by polyribosomes in the perikaryon of the nerve cells. Furthermore, it is linked to peripherally located ribosomes by means of filaments, 70 Å in diameter. A possible function in protein synthesis of structural components, such as neurofilaments, is hypothesized. Two distinctive fibrillar areas were identified in the nucleolus according to the tightness with which fibrils were packed together. Their significance is discussed. Nucleolar extrusions were never observed in our studies. Paranucleolar and coiled bodies were identified in the nuclear sap. The mechanism of formation and the significance of these bodies are discussed.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1007/BF00331464
