ISSN:
1432-0878
Keywords:
Thyroid gland
;
Calcitonin cells (C-cells)
;
Follicular cells
;
Immunoperoxidase reaction
;
Point-counting method
;
Rat (Wistar)
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary The development of calcitonin cells (C-cells) was investigated in rat thyroid glands from birth to 120 days, using an immunoperoxidase technique and a point-counting method. The proportion of C-cells to follicular cells was 4.5% on the day of birth and increased progressively to 10.4% by 120 days. The highest density of C-cells was noted in the mid-region of the lobes along a longitudinal axis. The caudal and cephalic regions of the lobes contained smaller numbers of C-cells. The C-cells tended to be more numerous in the posterior aspects of the lobes. Although the numbers of C-cells in 120-day-old animals were markedly increased as compared to animals at the time of birth, the cell distributions within the glands were similar at all ages.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00381881
