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  • 1
    ISSN: 1433-2965
    Keywords: Back pain ; Bone mineral density ; Osteoporosis ; Radiographic morphometry ; Stature ; Vertebral deformity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Bone mineral density (BMD) was measured in the lumbar spine using dual-energy X-ray absorptiometry in 222 unscreened women (aged 50–82 years), and information on back pain and historic loss of standing height was obtained at interview. Vertebral morphometry was performed on lateral spinal radiographs. The shape of the vertebral body was quantified using appropriate vertebral shape indices (VSIs), and vertebral deformities were identified using thresholds defined in terms of the means (M) and standard deviations (SD) of these VSIs for the whole group. Severity of deformity was defined as either grade 1 (M+2SD〈VSI〈M+3SD), grade 2 (M+3SD〈VSI〈M+4SD or grade 3 (VSI〉M+4SD). Subjects with grade 1 vertebral deformities were older than subjects without such deformities, but did not have a reduced age-related Z-score of BMD. Grade 2 wedge and concave deformities were associated with a reduced age-relatedZ-score of BMD, suggesting that the aetiology of such deformities is closest to conventional concepts of ‘osteoporotic fracture’. Grade 3 deformities were associated with neither increased age nor decreased BMD. Stature decreased in these subjects with age. Subjects reporting historic height loss had a higher mean number of wedge deformities. Subjects with back pain did not have a higher incidence of vertebral deformity than subjects without, confirming that many deformities were asymtomatic. Neither back pain nor historic loss of height were found to be associated with low spinal BMD.
    Type of Medium: Electronic Resource
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