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The occurrence of chondroitin-6-sulphate in adult human compact bone tissue (1979)

Hjerpe, A. ; Reinholt, F. P. ; Engfeldt, B.

Springer

Calcified tissue international 29 (1979), S. 169-171

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ISSN: 1432-0827

Keywords: Glycosaminoglycans ; Bone

Source: Springer Online Journal Archives 1860-2000

Topics: Biology , Medicine , Physics

Notes: Summary Compact bone tissue chondroitin sulphate, previously considered to be pure chondroitin-4-sulphate, was isolated from three adult human femoral diaphyses and digested with chondroitinase ABC. Assaying these digests by means of high performance liquid chromatography we could demonstrate that 12 to 14% of the disaccharide residues were 6-sulphated. The 4/6-ratios were also studied in chondroitin sulphate fractions of different molecular size. Slightly increasing amounts of 6-sulphated disaccharides were found with increasing size of the chondroitin sulphates.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF02408073

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