ISSN:
1860-1499
Keywords:
Subarachnoid hemorrhage
;
Calcium
;
Cerebral vasospasm
;
Electron microscopy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract In order to clarify the relationship between calcium mobilization and morphological changes in the arterial wall after subarachnoid hemorrhage, electron microscopic histochemical assessments of the intracellular calcium in the arterial wall of human subjects showing vasospasm angiographically were conducted. Intracellular calcium ions in the arterial wall after subarachnoid hemorrhage were significantly more numerous than those of the control specimens. However, reaction products of calcium ions in the arterial wall were distributed mainly in the areas which morphologically revealed spastic changes such as myonecrosis and vacuoles, and there were no or extremely few reaction products of calcium ions in the areas showing no morphological changes in the arterial wall. These findings were consistent with the data for a feline model with experimental subarachnoid hemorrhage previously studied by the authors and indicated that increased intracellular calcium mobilization detected histochemically might be related to the morphological changes in the arterial wall after subarachnoid hemorrhage.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02347971
