ISSN:
1432-8798
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The skin lesions of varicella were studied by electron microscopy. Singlemembrane particles were the only type of viral particles present in the nucleus. Two modes of viral envelopment were observed; budding from the inner nuclear membrane, and budding from vacuole membranes of the cytoplasm. Tubular, filamentous structures, probably an aberrant form of the virus, were often observed in affected nuclei. Nuclear bodies were frequently found and showed abnormal structures in the nuclei of cells near the intraepidermal vesicles. Strands, inclusion-like structures, probably composed of degenerated nuclear materials, were seen in some instances in the cytoplasm. Virions were frequently included in phagosomes of epidermal or dermal macrophages.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01250289
