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  • 1
    Electronic Resource
    Electronic Resource
    Viscosity-density gradient for purification of foot-and-mouth disease virus (1972)
    Springer
    Archives of virology 36 (1972), S. 141-146 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A simple and unique negative viscosity —positive density gradient has been devised which enables an effective single step purification of foot-and-mouth disease virus (FMDV) directly from cytoplasmic lysates. Using this gradient system, the recovery of infectious virus was greater than 95%. In addition, the isolated viral preparation was virtually free of contaminating cellular macromolecules. Further, the ratio of the volume of sample to gradient could be varied up to about two with a high degree of recovery and concentration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01250304
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