ISSN:
1438-2199
Keywords:
Amino acids
;
SOD-like activity
;
Cu (III)-Poly-L-lysine
;
Cu(III)-Poly-L-glutamic acid
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary The SOD-like activity of Cu(III) -complexes with polypeptides poly-L-lysine and poly-L-glutamic acid respectively was investigated. The Cu(II)-polypeptide complexes were first oxidized by K2IrCl6 to give the corresponding Cu(III) -compounds. The oxidation of Cu(II) and the corresponding Cu(II)/Cu(III) potential was evaluated by cyclic voltammetry (c.v.), UV-Vis and EPR spectroscopic (r.t.) experiments. Spin trapping EPR spectra were also conducted to confirm the formation of the superoxide radical. The SOD-like activity of each Cu(III)-complex was proved using the nitro blue tetrazolium (NBT) method slightly modified.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01388180
