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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Basic research in cardiology 74 (1979), S. 604-610 
    ISSN: 1435-1803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Es wird eine Methode beschrieben zur kontinuierlichen Messung des extrazellulären Raumes in isolierter Ventrikelmuskulatur. Die Größe des Extrazellulärraumes variiert mit dem kontraktilen Zustand des Muskels. Eingriffe wie Stillstellung, Mangan und Azidose reduzieren die Kontraktilität und vergrößern den Extrazellulärraum. Barium, Ouabain und Hypoxie verursachen Kontraktur und verkleinern den Extrazellulärraum. Diese Änderungen sollten berücksichtigt werden, wenn intrazelluläre Elektrolyte in isolierten Ventrikelpräparaten bestimmt werden.
    Notes: Summary A method is described with which the extracellular space of isolated ventricular muscle can be measured accurately and continuously in the same muscle. The size of the extracellular space is shown to vary with the contractile state of the myocardium. Interventions such as quiescence, manganese and acidosis reduce myocardial contractility and increase the size of the extracellular space. Barium, ouabain and hypoxia cause contracture and reduce the size of the extracellular space. These changes should be taken into account when measuring intracellular electrolytes in isolated ventricular preparations.
    Type of Medium: Electronic Resource
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